Hai Yu       Ph.D. ,associate professor       OFFICE ADDRESS:           Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS)        No.518, Ziyue Road, Minhang District, Shanghai 200241  Tel.: +86-21-34293773  Fax: +86-21-54081818  Email: haiyu_008@126.com       EDUCATION: 2002-2005    M. S.    Shandong Agricultural University, China 2005-2008   Ph.D.   Graduate School of CAAS & National Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, China       FACULTY APPOINTMENTS: 2008-2011   Assistant Professor, Division of Swine Infectious Disease, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences 2011-2012   Associate Professor, Division of Swine Infectious Disease, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences 2012-2013   Visiting Scholar, Department of Diagnostic Medicine/Pathobiology, College of veterinary Medicine, Kansas State University, Manhattan, KS, USA 2013-       Innovation Team for Ecology and Virology of Animal Influenza Virus, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences       PUBLICATION LISTS: 1. Hai Yu, Gui-Hong Zhang, Rong-Hong Hua, Qiang Zhang, Tian-Qiang Liu, Ming Liao, Guang-Zhi Tong*. Isolation and genetic analysis of human origin H1N1 and H3N2 influenza viruses from pigs in China. Biochem. Biophys. Res. Commun. 2007, 356: 91-96. 2. Hai Yu, Rong-Hong Hua, Qiang Zhang, Tian-Qiang Liu, Hui-Li Liu, Guo-Xin Li, Guang-Zhi Tong*. Genetic evolution of swine influenza A (H3N2) in China from 1970 to 2006. Journal of Clinical Microbiology. 2008, 46: 1067-1075. 3. Hai Yu, Rong-Hong Hua, Tian-Chao Wei, Yan-Jun Zhou, Zhi-Jun Tian, Guo-Xin Li, Tian-Qiang Liu, Guang-Zhi Tong*. Isolation and genetic characterization of avian origin H9N2 influenza viruses from pigs in China. Veterinary Microbiology. 2008, 131: 82-92. 4. Hai Yu, Yan-Jun Zhou, Guo-Xin Li, Gui-Hong Zhang, Hui-Li Liu, Li-Ping Yan, Ming Liao, Guang-Zhi Tong*. Further evidence for infection of pigs with human-like H1N1 influenza viruses in China. Virus Research. 2009, 140: 85-90. 5. Hai Yu, Peng-Chao Zhang, Yan-Jun Zhou, Guo-Xin Li, Jie Pan, Li-Ping Yan, Xiao-Xiao Shi, Hui-Li Liu, Guang-Zhi Tong. Isolation and genetic characterization of avian-like H1N1 and novel ressortant H1N2 influenza viruses from pigs in China. Biochem. Biophys. Res. Commun. 2009, 386: 278-283. 6. Hai Yu, Yan-Jun Zhou, Guo-Xin Li, Ji-Hong Ma, Li-Ping Yan, Bin Wang, Fu-Ru Yang, Meng Huang, Guang-Zhi Tong. Genetic diversity of H9N2 influenza viruses from pigs in China: a potential threat to human health? Veterinary Microbiology. 2011, 149:254-261. 7. Feng Wen, Hai Yu*, Furu Yang, Meng Huang, Shen Yang, Yanjun Zhou, Zejun Li, Guangzhi Tong*. Efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the Classical swine H1N1 subtype influenza virus in mice and pigs. Archives of virology. 2014, 159(11):2957-67. 8. Feng Wen, Jihong Ma, Hai Yu*, Furu Yang, Meng Huang, Yanjun Zhou, Zejun Li, Guangzhi Tong*. Protective efficacy of a high-growth reassortant swine H3N2 inactivated vaccine constructed by reverse genetic manipulation. Journal of veterinary science. 2014, 15(3):381-8. 9. Feng Wen, Ji-Hong Ma, Hai Yu*, Fu-Ru Yang, Meng Huang, Yan-Jun Zhou, Ze-Jun Li, Xiu-Hui Wang, Guo-Xin Li, Yi-Feng Jiang, Wu Tong, Guang-Zhi Tong*. A novel M2e multiple antigenic peptide providing heterologous protection on mice. Journal of veterinary science. 2015, Accepted. 10. Yan-Jun Zhou, Hai Yu, Zhi-Jun Tian, Guo-Xin Li, Xiao-Fang Hao, Li-Ping Yan, Jin-Mei Peng, Tong-Qing An, Ao-Tian Xu, Ya-Xin Wang, Tian-Chao Wei, Shan-Rui Zhang, Xue-Hui Cai, Li Feng, Xi Li, Gui-Hong Zhang, Lun-Jiang Zhou, Guang-Zhi Tong. Genetic diversity of the ORF5 gene of porcine reproductive and respiratory syndrome virus isolates in China from 2006 to 2008. Virus Research 2009, 144:136-144. 11. Yan-Jun Zhou, Hai Yu, Zhi-Jun Tian, Jin-Xia Liu, Tong-Qing An, Jin-Mei Peng, Guo-Xin Li, Yi-Feng Jiang, Xue-Hui Cai, Qiang Xue, Mei Wang, Yun-Feng Wang, Guang-Zhi Tong. Monoclonal antibodies and conserved antigenic epitopes in the C terminus of GP5 protein of the North American type porcine reproductive and respiratory syndrome virus. Veterinary Microbiology. 2009, 138:1-10. 12. Guo-Xin Li, Zhi-Jun Tian, Hai Yu, Yuan-Yuan Jin, Shao-Hua Hou, Yan-Jun Zhou, Tian-Qiang Liu, Shou-Ping Hu, Guang-Zhi Tong*. Fusion of C3d with hemagglutinin enhances protective immunity against swine influenza virus. Research in Veterinary Science. 2009, 86: 406-413. 13. Shen Yang, Xiaodu Wang, Lin Guo, Yafeng Qiu, Xiangdong Li, Hai Yu, Hua Xiang, Guang-Zhi Tong, Zhiyong Ma*. Influenza A virus induces p53 accumulation in a biphasic pattern. Biochem. Biophys. Res. Commun. 2009, 382: 331-335. 14. Guo-Xin Li,Yan-Jun Zhou, Hai Yu, Zhi-Jun Tian, Li-Ping Yan, Qiang Zhang, Shou-Ping Hu, Guang-Zhi Tong. Prime-boost immunization with HA/C3d DNA followed by a recombinant pseudorabies virus boost enhanced protective immunity against H3N2 swine influenza virus in mice. Research in Veterinary Science. 2010, 88:345-351 15. Ao-Tian Xu ,Yan-Jun Zhou, Guo-Xin Li, Hai Yu, Li-Ping Yan, Guang-Zhi Tong. Characterization of the biochemical properties and identification of amino acids forming the catalytic center of 3C-like proteinase of porcine reproductive and respiratory syndrome virus. Biotechnology Letters. 2010, 32: 1905-1910. 16. Ya-Xin Wang, Yan-Jun Zhou, Guo-Xin Li, Shan-Rui Zhang, Yi-Feng Jiang, Ao-Tian Xu, Hai Yu, Meng-Meng Wang, Li-Ping Yan, Guang-Zhi Tong. Identification of immunodominant T-cell epitopes in membrane protein of highly pathogenic porcine reproductive and respiratory syndrome virus. Virus Res. 2011, 158(1-2):108-15. 17. Shan-Rui Zhang, Yan-Jun Zhou, Yi-Feng Jiang, Guo-Xin Li, Li-Ping Yan, Hai Yu, Guang-Zhi Tong. Generation of an infectious clone of HuN4-F112, an attenuated live vaccine strain of porcine reproductive and respiratory syndrome virus. Virol J. 2011, 19;8:410. 18. Guo-Xin Li, Yan-Jun Zhou, Hai Yu, Ling Li, Ya-Xin Wang, Wu Tong, Jun-Wei Hou, Yan-Zhao Xu, Jian-Ping Zhu, Ao-Tian Xu, Guang-Zhi Tong. A novel dendrimeric peptide induces high level neutralizing antibodies against classical swine fever virus in rabbits. Vet Microbiol. 2012, 23;156(1-2):200-4.