一、个人简历

孙英杰，博士，研究员，博士生导师，现任禽病研究室副主任、国家级人才，十四五青年科学家项目主持人，入选中国农业科学院杰出青年英才、上海领军人才“后备队”。福建农林大学兼职博士生导师、上海微生物学会兽医微生物专业委员会主任、中国畜牧兽医学会公共卫生分会常务理事、中国畜牧兽医学会禽病学分会理事、J Gen Virol编辑、J Integr Agr青年编委。主要研究方向是动物副黏病毒的共性致病机制。重点关注病毒感染后诱导的固有免疫反应、代谢调控、细胞器应激以及细胞死亡等生物过程，深入探讨其在病毒复制和致病过程中的作用。主持国家重点研发计划青年科学家项目等国家和省部级项目8项。以第一或通讯作者在Cell Reports、Autophagy (3)、Plos Pathogens (3)、mBio (2)、Journal of Advanced Research、Journal of Virology (6)、iScience、FASEB Journal等SCI期刊发表论文30篇，获授权发明专利11件，获“王泽霖基金禽病研究创新奖”。

二、联系方式

邮      箱：sunyingjie@shvri.ac.cn

三、代表论著

[1] Mengqing Yang, Juan Chen, Xiang Su, Xianjin Kan, Lei Tan, Cuiping Song, Xusheng Qiu, Ying Liao, Shengqing Yu, Chan Ding*, Yingjie Sun*, Lipophagy fuels phosphatidylcholine synthesis for Newcastle disease virus replication, Autophagy, 2026 Mar 11:1-18.

[2] Yang Qu, Shanhui Ren, Ying Liao, Xusheng Qiu, Lei Tan, Cuiping Song, Yingjie Sun*, Chan Ding*, Newcastle disease virus hijacks mitophagy to reprogram amino acid metabolism for enhanced replication, Autophagy, 2026 Feb 12:1-19.

[3] Yanfeng Liu, Zhongyuan Liu, Xiaoqing Ou, Feiyang Zhao, Jingrui Wang, Yang Qu, Xusheng Qiu, Ying Liao, Lei Tan, Cuiping Song, Chan Ding, Yingjie Sun*, Caspase-mediated DDX46 cleavage unchains antiviral immunity, mBio, 2026.

[4] Hui Jiang, Yang Qu, Xianjin Kan, Mengqing Yang, Yabin Gong, Ying Liao, Xusheng Qiu, Lei Tan, Cuiping Song, Venugopal Nair, Chan Ding*, Yingjie Sun*, Pexophagy-driven redox imbalance promotes virus-induced ferroptosis, Cell Reports, 2025, 44(6): 115783.

[5] Yongqi Guo, Menghang Wang, Ning Tang, Yubo Zhao, Lijing Wo, Dexin Liang, Rui Huangª, Yandong Tang*, Yingjie Sun*, Xin Yin*, Antimycin A inhibits alpha-herpesvirus replication by disrupting the formation of pyrimidinosomes, Journal of Advanced Research, 2025.

[6] Yang Qu, Siyuan Wang, Hui Jiang, Ying Liao, Xusheng Qiu, Lei Tan, Cuiping Song, Venugopal Nair, Zengqi Yang*, Yingjie Sun*, Chan Ding*, Newcastle disease virus infection induces parthanatos in tumor cells via calcium waves, Plos Pathogens, 2024, 20(12): e1012737.

[7] Changrun Zhao, Ning Tang, Jing Wang, Yang Qu, Lei Tan, Cuiping Song, Xusheng Qiu, Ying Liao, Tingrong Luo, Chan Ding, Yingjie Sun, p53-mediated regulation of electron transport chain and nucleotide synthesis during Newcastle disease virus infection. J Virol. 2025, 99(11):e0157625.

[8] Yifan Sun, Lanlan Tang, Xianjin Kan, Lei Tan, Cuiping Song, Xusheng Qiu, Ying Liao, Venugopal Nair, Chan Ding*, Xiufan Liu*, Yingjie Sun*, Oncolytic Newcastle disease virus induced degradation of YAP through E3 ubiquitin ligase PRKN to exacerbate ferroptosis in tumor cells, Journal of Virology, 2024, 98(3): e0189723.

[9] Hui Jiang, Yanfeng Liu, Ying Liao, Xusheng Qiu, Lei Tan, Cuiping Song, Chan Ding*, Yingjie Sun*, PEX5-mediated modulation of apoptotic pathways in response to Newcastle disease virus infection, Journal of Integrative Agriculture, 2024.

[10] Wei Wu, Yang Qu, Shengqing Yu, Sa Wang, Yuncong Yin, Qinfang Liu, Chunchun Meng, Ying Liao, Zaib Ur Rehman, Lei Tan, Cuiping Song, Xusheng Qiu, Weiwei Liu, Chan Ding*, Yingjie Sun*, Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity, mBio, 2021, 12(3): e0100521.

四、专利标准

[1] A COMPOSITE MULTI-EPITOPE EXPRESSION CASSETTE, A RECOMBINANT VIRUS COMPOSED THEREOF AND APPLICATION THEREOF, 授权时间：2022.04.19，美国专利号：US 11,305,007,B2

[2] 一种尼帕病毒N蛋白特异性的单克隆抗体及其制备方法和应用。授权时间：2025.23.30，中国专利号：ZL 202411676201.3.

[3] 一种重组表达载体、制备得到的I型鸭甲型肝炎病毒样颗粒、制备方法及应用。授权时间2023.05.05，中国专利号：ZL201910603170

[4] 一种复合多表位表达盒、其组成的重组病毒及应用。授权时间：2023.06.30，中国专利号：ZL202011211170.

[5] 一种表达Furin蛋白的细胞株及其在禽传染性支气管炎病毒培养中的应用。授权时间：2021.8, 中国专利授权号：ZL201910344592.1

[6] 稳定表达仓鼠TIGAR基因的BHK细胞系及其构建方法和应用。授权时间：2021.8, 中国专利授权号：ZL201910344592.1

[7] 一种鹅源线粒体抗病毒信号蛋白及其应用，2021-08-03，中国，ZL201810367202.8

[8] 一种具有抗新城疫病毒活性的鹅源基因RIG-I及应用，2015-12-22，中国，ZL201210281895.1