一、个人简历

金亚美，博士研究生，研究员，博士/硕士生导师。长期从事血吸虫生殖发育机理，血吸虫与宿主相互关系等方向的研究，主持国家自然科学基金项目2项，上海自然科学基金2项，教育部、人事部留学人员基金各1项，农科院基本科研业务项目4项，培养（含联合培养）博士生5名、硕士生18名。以第一或通讯作者在《PLoS Pathogens》《International Journal for Parasitology》《Acta Tropica》《Veterinary Reseach》等国内外发表论文50余篇，其中SCI论文30余篇，获专利5项。

二、联系方式

办公电话：086-18621919182

邮   箱：yameijin@shvri.ac.cn

三、代表论著

1. Zhong H, Dong B, Zhu D, Fu Z, Liu J, Guan G, Jin Y*. RNA sequencing analysis reveals the impact of Schistosoma japonicum worm on host liver fibrosis. Acta Trop. 2025，270:107747. doi: 10.1016/j.actatropica.2025.107747. PMID: 40680920

2. Zhong H, Zhu D, Dong B, Li H, Fu Z, Liu J, Guan G, Jin Y*. Role of sja-let-7 in egg production and reproductive development in female Schistosoma japonicum. Acta Trop. 2025 Aug;268:107724. doi: 10.1016/j.actatropica.2025.107724. PMID: 40609849

3. Zhong H, Zhu D, Dong B, Wu L, Lu K, Fu Z, Liu J, Guan G, Jin Y*. Comparative microRNAs profile of Schistosoma japonicum male worms derived from single-sex and bisexual infections: Implications of the multifunctional role of microRNA. Parasitol Res. 2025，124(4):43. doi: 10.1007/s00436-025-08489-x. PMID: 40272512

4. Zhong H, Dong B, Zhu D, Fu Z, Liu J, Jin Y*. Sja-let-7 suppresses the development of liver fibrosis via Schistosoma japonicum extracellular vesicles. PLoS Pathog. 2024，20(4):e1012153. doi: 10.1371/journal.ppat.1012153. PMID: 38598555

5. Zhong H, Hou L, Qin F, Ren Y, Dong B, Zhu D, Li H, Lu K, Fu Z, Liu J, Gu S, Jin Y*. Molecular and functional characterization of Schistosoma japonicum annexin A13. Vet Res. 2023, 54(1):116. doi: 10.1186/s13567-023-01244-z.PMID: 38049816

6. Zhong H, Qin F, Ren Y, Li X, Hou L, Gu S, Jin Y*. Functional characterization of differentially expressed proteins coming from unisexual and bisexual infected Schistosoma japonicum female worms. Exp Parasitol. 2023, 248:108504. doi: 10.1016/j.exppara.2023.108504. PMID: 36914063

7. Zhong H, Wu L, Ren Y, Qin F, Jin Y*. Comparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections. Int J Parasitol. 2022 Dec;52(13-14):815-828. doi: 10.1016/j.ijpara.2022.09.005. PMID: 36265673

8. Ren Y, Li M, Shi Y, Liu P, Wu Q, Yang Y, Zhang L, Jin Y*. Schistosoma japonicum proteins that interact with the gynecophoral canal protein identified using a yeast two-hybrid system. Exp Parasitol. 2022 Aug;239:108305. doi: 10.1016/j.exppara.2022.108305. PMID: 35714725

9. Zhong H, Ren Y, Qin F, Li X, Hou L, Gu S, Jin Y*. Schistosoma japonicum translationally controlled tumour protein, which is associated with the development of female worms, as a target for control of schistosomiasis. Int J Parasitol. 2022 Jul;52(8):569-579. doi: 10.1016/j.ijpara.2022.01.005. PMID: 35318950

10. Han Y, Feng J, Ren Y, Wu L, Li H, Liu J, Jin Y*. Differential expression of microRNA between normally developed and underdeveloped female worms of Schistosoma japonicum. Vet Res. 2020 Sep 25;51(1):126. doi: 10.1186/s13567-020-00851-4. PMID: 32977838

11. Cheng G, Li X, Qin F, Xu R, Zhang Y, Liu J, Gu S, Jin Y*. Functional analysis of the Frzb2 gene in Schistosoma japonicum. Vet Res. 2019 Dec 11;50(1):108. doi: 10.1186/s13567-019-0716-1. PMID: 31829289

12. Li X, Qiao H, Qin F, Cheng G, Liu J, Li H, Gu S, Jin Y*. Comparative analysis of iTRAQ-based proteome profiles of Schistosoma japonicum female worms coming from single-sex infections and bisexual infections. J Proteomics. 2020 Feb 20;213:103597. doi: 10.1016/j.jprot.2019.103597. PMID: 31778827

13. Li X, Cheng G, Qin F, Liu J, Li H, Jin Y*. Function of the lesswright (lwr) gene in the growth, development, and reproduction of Schistosoma japonicum. Vet Parasitol. 2019 Aug;272:31-39. doi: 10.1016/j.vetpar.2019.06.010. PMID: 31395202

四、专利标准

1. 日本血吸虫SjFrzb2基因的siRNA及其应用,2023-01-06, 中国, ZL201910499739.4

2. 日本血吸虫SjELAV-like2基因的siRNA及其应用, 2022-06-21, 中国, ZL201810458759.5

3. 日本血吸虫SjELAV-like1基因的siRNA及其应用, 2022-06-21, 中国, ZL201810498888.4

4. 日本血吸虫SjLGL基因的siRNA及其应用, 2012-10-31, 中国, ZL201110139530.0

5. 日本血吸虫蛋白质及其应用, 2013-10-09, 中国, ZL201010575768.3