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人才队伍

邱亚峰


研究领域:病原微生物感染与免疫
电话/传真:021-34680292(O);021-54081818(F)
电子邮件:yafengq@shvri.ac.cn

简历(200-500字):
邱亚峰,博士,研究员,博士生导师。中国农业科学院“青年英才计划”入选者。2001年毕业于山东农业大学,获学士学位(兽医专业);2006年毕业于南京农业大学,博士学位(兽医传染病专业);2006年到中国农业科学院上海兽医所工作,任助理研究员;2009年1月起,任副研究员;2011年-2013年,在密西根大学医学院从事博士后研究;2014年1月-至今,在中国农业科学院上海兽医所工作,任研究员。
现从事病原微生物感染与免疫的基础研究,主要以兽医临床上常见的猪圆环病毒、猪繁殖与呼吸综合征病毒、副猪嗜血杆菌、胸膜肺炎防线杆菌等病原微生物为研究模型,旨在揭示病毒感染继发细菌感染的免疫分子机制;另外,以日本乙型脑炎病毒为模式病原微生物,研究日本乙型脑炎病毒感染的免疫致病机制。

获奖及荣誉:
广西科学技术奖(自然科学奖),三等奖(2013-Z-3-009-04),排名为第四。

承担科研项目情况:
1,中国农业科学院“青年英才计划”资助项目,2015-2018,主持。
2,上海市自然基金项目(15ZR1449800),2015.1-2017.12,主持。
3,中国农业科学院基本科研业务费预算增量项目(2015ZL065),2015.1-2015.12,主持。
4,上海市科技兴农重点攻关项目“上海地区H9N2亚型禽流感病毒生物学特性及病毒样颗粒的研究”,2015.4-2018.3,参加。

代表论著:
1.Qiu, Y.F., Dayrit, J.K., Davis, M.J., Carolan, J.F., Osterholzer, J.J., Curtis, J.L., and Olszewski, M.A. (2013). Scavenger Receptor A Modulates the Immune Response to Pulmonary Cryptococcus neoformans Infection. The Journal of Immunology 191(1): 238-48.
2.Qiu, Y.F., Zeltzer, S., Zhang, Y.M., Chen, G.H., Dayrit, J.K., Murdock, B.J., Bhan, U., Toews, G.B., Osterholzer, J.J., Standiford, T.J., and Olszewski, M.A. (2012). Early Induction of CCL7 Downstream of TLR9 Signaling Promotes the Development of Robust Immunity to Cryptococcal Infection. The Journal of Immunology 188(8):3940-8.
3.Qiu, Y.F., Davis, M.J., Dayrit, J.K., Hadd, Z., Meister, D.L., Osterholzer, J.J., Williamson, P.R., and Olszewski, M.A. (2012). Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice. PLoS ONE 7(10): e47853. 
4.Eastman, A.J., He, X.M., Qiu, Y.F., Davis, M.J., Vedula, P., Lyons, D.M., Park, Y.D., Hardison, S.E., Malachowski, A.N., Osterholzer, J.J., Wormley, FL Jr, Williamson, P.R., Olszewski, M.A. (2015). Cryptococcal Heat Shock Protein 70 Homolog Ssa1 Contributes to Pulmonary Expansion of Cryptococcus neoformans during the Afferent Phase of the Immune Response by Promoting Macrophage M2 Polarization. The Journal of Immunology 194(12):5999-6010.
5.Davis, M.J., Eastman, A.J., Qiu, Y.F., Gregorka, B., Kozel, T.R., Osterholzer, J.J., Curtis, J.L., Swanson, J.A., and Olszewski, M.A. (2015). Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal Virulence. The Journal of Immunology 194(5): 2219-2231.
6.Davis, M.J., Tsang, T.M., Qiu, Y.F., Dayrit, J.K., Freij, J.B., Huffnagle, G.B., and Olszewski, M.A. (2013). Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection. mBio 4(3): e00264-13.
7.Wang, X.D., Deng, X.F., Yan, W.J., Zhu, Z.Q., Shen, Y., Qiu, Y.F., Shi, Z.X., Shao, D.H., Wei, J.C., Xia, X.Z., and Ma, Z.Y. (2012). Stabilization of p53 in influenza A virus-infected cells is associated with compromised MDM2-mediated ubiquitination of p53. The Journal of Biological Chemistry 287(22):18366-75. 
8.Deng, X.F., Shi, Z.X., Li, S.Q., Wang, X.D., Qiu, Y.F., Shao, D.H., Wei, J.C., Tong, G.Z., and Ma, Z.Y. (2011). Characterization of nonstructural protein 3 of a neurovirulent Japanese encephalitis virus strain isolated from a pig. Virology Journal 8:209.
9.Ge, F.F., Qiu, Y.F., Yang, Y.W., and Chen, P.Y. (2007). An hsp70 fusion protein vaccine potentiates the immune response against Japanese encephalitis virus. Archives of virology 152(1):125-135.
10.Ge, F.F., Qiu, Y.F., Gao, X.F., Yang, Y.W., and Chen, P.Y. (2006). Fusion expression of major antigenic segment of JEV E protein-hsp70 and the identification of domain acting as adjuvant in hsp70. Veterinary immunology and immunopathology 113(3-4):288-96.