Feiqun Xue2015-11-26
FEIQUN XUE
Ph. D, Professor
E-mail:fqxun@shvri.ac.cn
Tel: 021-34293460 (O)
Address: No. 518, Ziyue Road, Minhang District, Shanghai, 200241, China;
Education
1991-1994 PhD, Physical Chemistry, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China
1978-1982 BD, Department of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
Professional Experience
2014- Present, Chief-scientist of new veterinary drugs Research Group, Shanghai Veterinary Research Institute, CAAS
2000-2013, Dean of Department of Pharmacy, Shanghai Veterinary Research Institute, CAAS
1995-2000, Professor, veterinary drug research, Lanzhou Institute of Husbandry and Pharmaceutical sciences, CAAS
Current Research Topics
Synthesis of chemical drugs
The relationship between structure and activity
Research new dosage forms
studys for Veterinary drug residue and safety evaluation
Publications
[1] Bianhua Zhou, Hongwei Wang, Feiqun Xue, Xiaoyang Wang, Chenzhong Fei, et al. Effects of diclazuril on apoptosis and mitochondrial transmembrane potential in second-generation merozoites of Eimeria tenella. Veterinary Parasitology, 2010, 168(3-4):217-222.
[2] Bianhua Zhou, Hongwei Wang, Feiqun Xue, Xiaoyang Wang, Fengkun Yang, Manman Ban, Ruixiang Xin, Congcong Wang. Actin-depolymerizing factor of second-generation merozoite in Eimeria tenella: clone, prokaryotic expression, and diclazuril-induced mRNA expression. Parasitology Research, 2010, 106(3):571-576.
[3] Zhanzhong Zhao, Lifang Zhang, Feiqun Xue, Tao Zhang. Metabolic profile of nitazoxanide in goat feces. Chromatographia, 2008, 68(9-10):731-738.
[4] Zhanzhong Zhao, Jian Wang, Peihong Liu, Suhua Zhang, Jianpei Gong, Xiqin Huang, Bin Li, Feiqun Xue. Cultivation, LD50 determination and experimental model of Streptococcus suis serotype 2 strain HA9801. Research in Veterinary Science, 2009, 86(2):200-205.
[5] Zhanzhong Zhao, Feiqun Xue, Lifang Zhang, keyu zhang, chenzhong fei, wenli zheng, et al. The pharmacokinetics of nitazoxanide active metabolite (tizoxanide) in goats and its protein binding ability in vitro. J Vet Pharmacol Ther, 2010, 33(2):147-53.
[6] Bian-hua Zhou, Hong-wei Wang, Xiao-yang Wang, Li-fang Zhang, Ke-yu Zhang, Fei-qun Xue. Eimeria tenella: Effect of diclazuril treatment on microneme genes expression in second- generation merozoite and pathological changes of caeca in parasitized chickens. Experimental Parasitology. 2010. 125:264-270.
[7] Zhanzhong Zhao, Lifang Zhang, Feiqun Xue, et al. Liquid chromatography– tandem mass spectrometry analysis of nitazoxanide and its major metabolites in goat. Journal of Chromatography B, 2008, 875(2):427-436.
[8] Chengyuan Cai, Lifang Zhang, Feiqun Xue, Minqi Qiu, Wenli Zheng. Simultaneous determination of triclabendazole and its metabolites in bovine and goat tissues by liquid chromatography-tandem mass spectrometry. 2010. 878: 3106-12.
[9] Zhou Bian-hua, Shen Xiao-jiong, Wang Hong-wei Li Tao※,Xue Fei-qun※. Receptor for activated C kinase ortholog of second-generation merozoite in Eimeria tenella: clone, characterization,and diclazuril-induced mRNA expression. Parasitol Re. 2012; 111:1447-1455.
[10] Shen Xiao-jiong, Li Tao※, Fu Jian-jun, Zhang Ke-yu,Wang Xiao-yang, Liu Yin-chun, Zhang Hua-jing, Fan Chao, Fei Cheng-zhong, Xue Fei-qun※.Proteomic analysis of the effect of diclazuril on second-generation merozoites of Eimeria tenella. Parasitol Res. 2014;113:903–909.
[11] Xiaojiong Shen, Congcong Wang, Qingxu Zhu, Tao Li, Lijia Yu, Wenli Zheng,
Chenzhong Fei, Minqi Qiu, Feiqun Xue※.Effect of the diclazuril on Hsp90 in the second-generation merozoites of Eimeria tenella. Veterinary Parasitology. 2012; 185:290-295.