Xusheng Qiu   Ph.D Associate professor   E-mail: xsqiu1981@shvri.ac.cn Tel: 021-34293426 Address: No.518, Ziyue Road, Minhang District, Shanghai, 200241, China;   Education   2005-2009 PhD, Preventive Veterinary Medicine, University of Yangzhou, Yangzhou, China 2001-2004 Bachelor, Veterinary Medicine, University of Yangzhou, Yangzhou, China   Professional Experience   2012-Present, Associate Professor; Shanghai Veterinary Research Institute, CAAS 2009-2011, Assistant Professor; Shanghai Veterinary Research Institute, CAAS   Current Research Topics   1. 新城疫反向遗传平台的建立：  2.新城疫新型疫苗的研制：  3.开展长期的新城疫病毒的流行病学调查工作：  4. 研发新城疫病毒的检测技术：  5. 新城疫毒力进化机制的研究：  6. 开展新城疫拮抗先天性免疫的分子机制研究，揭示了新城疫病毒对水禽致病力弱的分子机制：   Reverse genetics of Newcastle diseases virus for novel vaccine development Establishment of rapid diagnosis technology and epidemiological surveillance of Newcastle diseases Research on the evolution of Newcastle diseases Pathogenicity, transmission and control of Newcastle diseases   Publications   1.Qiu X, Yu Y, Yu S, Zhan Y, Wei N, Song C, Sun Y, Tan L, Ding C. Development of Strand-Specific Real-Time RT-PCR to Distinguish Viral RNAs during Newcastle Disease Virus Infection. The Scientific World Journal. 1537-744X 2014 Oct 14. dx.doi.org/10.1155/2014/934851. 2.Xusheng Qiu, Qing Sun, Shuang Wu, Li Dong, Shunling Hu, Chunchun Meng, Yantao Wu, and Xiufan Liu. Entire genome sequence analysis of genotype IX Newcastle disease viruses reveals their early-genotype phylogenetic position and recent-genotype genome size，Virology Journal, 2011, 8:117 3.Meng, C., X. Qiu, S. Jin, S. Yu, H. Chen, and C. Ding. 2012. Whole genome sequencing and biological characterization of Duck/JS/10, a new lentogenic class I Newcastle disease virus. Arch Virol 157:869-880.  4.Yu, Y., X. Qiu, D. Xu, Y. Zhan, C. Meng, N. Wei, H. Chen, L. Tan, S. Yu, X. Liu, A. Qin, and C. Ding. 2012. Rescue of virulent class I Newcastle disease virus variant 9a5b-D5C1. Virol J 9:120.  5.Yingjie Sun, Shengqing Yu, Na Ding, Chunchun Meng, Songshu Meng, Shilei Zhang, Yuan Zhan, Xusheng Qiu, Lei Tan, Hongjun Chen, Cuiping Song, Chan Ding. Autophagy benefits the replication of Newcastle disease virus in chicken cells and tissues. Journal of Virology, 2013, 88(1):525–537. 6.Bao S, Guo X, Yu S, Ding J, Tan L, Zhang F, Sun Y, Qiu X, Chen G, Ding C. Mycoplasma synoviae enolase is a plasminogen/fibronectin binding protein. BMC Vet Res. 1746-6148 2014 Sep 25;10(1) 223-232. 7.Cuiping Song, Shengqing Yu, Yunbing Duan, Yue Hu, Xvsheng Qiu, Lei Tan,  Yingjie Sun, Mingshu Wang, Anchun Cheng, Chan Ding. Effect of age on the pathogenesis of DHV-1 in Pekin ducks and on the innate immune responses of ducks to infection. Arch Virol. 0304-8608 159 905-914. 8.Tan L, Hu M, Yu S, Wang X, Lu F, Liu F, Qiu X, Song C, Sun Y, Ding C. Characterization of the chaperonin GroEL in Mycoplasma gallisepticum. Arch Microbiol. 0302-8933 2014 Oct 11.  9.Song C, Liao Y, Gao W, Yu S, Sun Y, Qiu X, Tan L, Cheng A, Wang M, Ma Z, Ding C. Virulent and attenuated strains of duck hepatitis virus elicit discordant innate immune responses in vivo. J Gen Virol. 0022-1317 2014 Sep 12. pii: vir.0.070011-0. doi: 10.1099/vir.0.070011-0.  10.Cheng, J., Sun, Y., Zhang, X., Zhang, F., Zhang, S., Yu, S., Qiu, X., Tan, L., Song, C., Gao, S., Wu, Y., Ding, C. Toll-like receptor 3 inhibits Newcastle disease virus replication through activation of pro-inflammatory cytokines and the type-1 interferon pathway. Arch Virol. 0304-8608 2014 Nov;159(11) 2937-2948. 11.Zhang S, Sun Y, Chen H, Dai Y, Zhan Y, Yu S, Qiu X, Tan L, Song C, Ding C. Activation of the PKR/eIF2α signaling cascade inhibits replication of Newcastle disease virus. Virol J. 1743-422X 2014 Mar 31;11:62. doi: 10.1186/1743-422X-11-62. 12.Qing Sun, Lixiang Zhao, Qingqing Song, Zheng Wang, Xusheng Qiu, Wenjun Zhang, Mingjun Zhao, Guo Zh ao, Wenbo Liu, Haiyan Liu, Yunsen Li, and Xiuf an Liu. Hybrid- and Complex-type N-glycans are not Essential for Newcastle Disease Virus Infection and Fusion of Host Cells，Glycobiology，Glycobiology. 2012 Mar;22(3):369-78. 13.Song, C., H. Wan, S. Yu, X. Han, X. Qiu, Q. Hu, L. Tan, and C. Ding. 2012. Rapid detection of duck hepatitis virus type-1 by reverse transcription loop-mediated isothermal amplification. J Virol Methods 182:76-81. 14.Hongjun Chen, Shengqing Yu, Meirong Hu, Xiangan Han, Danqing Chen, Xusheng Qiu, Chan Ding. Identification of biofilm formation by Mycoplasma gallisepticum.Veterinary Microbiology. 2012, 161: 96–103. 15.Chen H, Yu S, Shen X, Chen D, Qiu X, Song C, Ding C: The Mycoplasma gallisepticum alpha-enolase is cell surface-exposed and mediates adherence by binding to chicken plasminogen. Microb Pathog 2011, 51:285-290. 16.Yingjie Sun, Na Ding, Siyu Serena Ding, Shengqing Yu, Chunhun Meng, Hongjun Chen, Xusheng Qiu, Shilei Zhang, Yang Yua, Yuan Zhan, Chan Ding. Goose RIG-I functions in innate immunity against Newcastle disease virus infections.Molecular Immunology. 2013, 53: 321– 327.