Zongyan Chen Ph.D. Associate Professor
Department of Avian diseases, Shanghai Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Shanghai, China
Phone: 021-34293426
Fax: 021-54082828
E-mail:zychen@shvri.ac.cn
Professional Training and Experience
l 2008-Pres. Faculty, Associate Professor
l 2014-2015. Guest Investigator, Department of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, College Park
l 2003-2008. Ph.D. in Avian Diseases and Molecular Biology, Sichuan Agricultural University, Yaan, China
Current Research Topics
l Identification of molecular determinants of reovirus/IBDV virulence
l Identification of the mechanisms of reovirus pathogenesis
l Molecular characterization of new and emerging waterflow diseases
l Vaccine Development
Publications
l Wu Qiaomei, Ding Mingyang, Li Chuanfeng, Liu Guangqing, Chen Zongyan*. Construction and characterization of an infectious molecular clone of novel duck reovirus. Journal of General Virology,2018 ;99(4) 449–4561.
l Dawei Xu, Chuanfeng Li, Guangqing Liu, Zongyan Chen*, Renyong Jia*. Generation and evaluation of a recombinant goose origin Newcastle disease virus expressing Cap protein of goose origin avastrovirus as a bivalent vaccine in goslings. Poultry Science, 2019(98):4426–4432.
l Xiaxia Du, Rong Xiao, Hualin Fu , Zhixiang Yuan , Wei Zhang , Lizi Yin , Changliang He , Chuanfeng Li , Jiewen Zhou , Guangqing Liu , Gang Shu*, Zongyan Chen*.Hypericin-loaded graphene oxide protects ducks against a novel duck reovirus. Materials Science & Engineering C,2019(105):1-8.
l Rong Xiao, Xiaoyun Mi, Jiahui Sun, Mingyang Ding, Chuanfeng Li, Jie Zhu, Guangqing Liu, Wenge Ma, Hailong Zhou , Zongyan Chen*. Interaction between Translocation-associated membrane protein 1 and σC protein of novel duck reovirus controls virus infectivity. Virus Genes, 2020, 56:347-353.
l Xiaxia DU, Mingyang Ding, Qiaomei Wu, Chuanfeng Li, Huimin Guo, Guangqing Liu, Zongyan Chen*. Characterization of a P18 Protein in the S1 Segment of the Novel Duck Reovirus Genome. Acta Virol,2020, 64(1),59-66.
l Cong Huang, Yuanling Huang, Zhiyi Liu, Jia Li, Jingyi Han, Yingnan Liu, Jingyi Liu, Hongjun Chen, Zongyan Chen*.Isolation and characterization of a duck reovirus strain from mature ducks in China.Poult Sci, 2023 ;102(2):102345.
l Yuanling Huang , Gang Shu, Cong Huang, Jingyi Han, Jia Li, Hongjun Chen, Zongyan Chen*. Characterization and pathogenicity of a novel variant infectious bursal disease virus in China.Front Microbiol, 2023,17;13:1039259.
l Xinjin Shi, Xinyu Zhang, Haiwei Sun, Changqing Wei, Yingnan Liu, Jiguan Luo, Xuebo Wang ,Zongyan Chen* , Hongjun Chen. Isolation and pathogenic characterization of duck adenovirus 3 mutant circulating in China.Poult Sci, 2022 Jan;101(1):101564.
l Zongyan Chen， Yingqi Zhu，Guangqing Liu. Outbreak associated Novel Duck Reovirus,China,2011.Emerging Infectious Diseases, 2012,18(7):1210-1213.
l Zongyan Chen, Chuanfeng Li，Yingqi Zhu,et al. Immunogenicity of virus-like particles containing modified goose parvovirus VP2 protein. Virus Research， 2012,169(1): 306-309.
l Zongyan Chen，Chuanfeng Li，Gaojing Peng，et al. Expression，purification，characterization and subcellular localization of the goose parvovirus Rep1 protein. Protein and Peptide Letter,2013,20(7):820-5.
l Zongyan Chen，Chuanfeng Li，Guoxin Li，et al. Rapid Diagnosis of Goose Viral Infections by Multiplex PCR. Journal of virological methods,2013, 191(2):101-4.
l Zongyan Chen, Anchun Cheng, Mingwhu Wang, Dawei Xu, Wen Zeng, Zhan Li. Antiviral effects of PNA in duck hepatitis B virus infection model.Acta Pharmacol Sin. 2007,28(10):1652-8.
l Zongyan Chen, Anchun Cheng, Mingshu Wang, Dawei Xu, Renyong Jia, Yufei Guo, Weng Zeng.Viral load in 1-day-old ducklings acutely infected with duck hepatitis B virus by different doses and routes of inoculation. Avian Pathol. 2009 Apr;38(2):129-34.