XINGANG FENG   Ph. D, Dept. of Animal Schistosomiasis Control Professor   E-mail: fengxingang@shvri.ac.cn Tel: 021-34293480 (O) Address: No. 518, Ziyue Road, Minhang District, Shanghai, 200241, China;   Education   1999.07-2001.08 post-doctoral, Molecular Parasitology, Dept. of Animal Schistosomiasis Control, Shanghai Veterinary Research Institute, CAAS, Shanghai, China 1996.9-1999.6 PhD, Molecular Parasitology, Dept of Pathogen Biol., Medical College，Sun Yat-sen University，Guangzhou, China  1985.9-1988.7 M.S, Protozoological Biology, Dept of Biol., East China Normal University, Shanghai, China.  1979.9–1983.6 B.S. General Biology, Dept of Biol, East China Normal University, Shanghai,China.   Professional Experience   2014.01-Present, Professor, Molecular biology and immunology on Schistosoma japonicum and Haemonchus contortus, Animal Schistosomiasis Control Research Group, Shanghai Veterinary Research Institute, CAAS 2008.01-2013.12, Professor, Molecular immunology and functional genomics on Schistosoma japonicum, Dept. of Animal Schistosomiasis Control, Shanghai Veterinary Research Institute, CAAS 2005.08-2007.12, Associate Professor; functional genomics on Schistosoma japonicum, deputy director at Shanghai Research Center for Animal Biotechnology, Shanghai Veterinary Research Institute, CAAS 2004.07-2008.07, visiting scholar, Graduate Center for Toxicology, the Graduate School, University of Kentucky, Kentucky, USA 2001.07-2004.06, Associate Professor; functional genomics on Schistosoma japonicum, deputy director at Shanghai Research Center for Animal Biotechnology, Shanghai Veterinary Research Institute, CAAS 1993.11-1996.08, Research Assistant, plant molluscicides research, Head, Dept of Biology, Hunan Institute of Parasitic Diseases (HIPD). Yueyang, Hunan, China 1988.9-1993.10 Research Assistant, Molluscicides research, Dept of Pharmacology, HIPD, Yueyang, Hunan, China 1983.07-1985.08, Teaching assistant, Dept of Biol., Shaoyang University, Shaoyang, Hunan,China   Current Research Topics   Cellular and molecular functions and mechanism of protective immunity induced by radiation-attenuated Schistosoma japonicum or Haemonchus contortus vaccines Functions and mechanism of helminth-derived immune regulatory molecules  Discovery and characterization of drug resistance genes or molecules from Haemonchus contortus using population genomics method      Publications   1.Duan MM , Xu RM,  Yuan CX,  Li YY,  Liu Q, Cheng GF,  Lin JJ,  Feng XG. SjHSP70, a recombinant Schistosoma japonicum heat shock protein 70, is immunostimulatory and induces protective immunity against cercarial challenge in mice.  Parasitol Res. 2015；114(9):3415-29. 2.Zhang YL, Li YY, Zhao BP, Yuan CX, Yang JM, Lin JJ, Feng XG. Molecular characterization and identification of Th1 epitopes of a Schistosoma japonicum protein similar to prosaposin. Parasitol Res. 2014;113(3):983-992.  3.Yang J, Hong Y, Yuan C, Fu Z, Shi Y, Zhang M, Shen L, Han Y, Zhu C, Li H, Lu K, Liu J, Feng X, Lin J. Microarray analysis of gene expression profiles of Schistosoma japonicum derived from less-susceptible host water buffalo and susceptible host goat.  PLoS One. 2013;8(8):e70367.  4.Zhang YL, Jia K, Zhao BP, Li Y, Yuan CX, Yang JM, Lin JJ, Feng XG. Identification of Th1 epitopes within molecules from the lung-stage schistosomulum of Schistosoma japonicum by combining prediction analysis of the transcriptome with experimental validation. Parasitol Int. 2012;61(4):586-593.  5.Zhao, B. P. Chen, L. Zhang, Y. L. Yang, J. M. Jia, K. Sui, C. Y. Yuan, C. X. Lin, J. J. Feng, X.G. In silico prediction of binding of promiscuous peptides to multiple MHC class-II molecules identifies the Th1 cell epitopes from secreted and transmembrane proteins of Schistosoma japonicum in BALB/c mice. Microbes and Infection  2011，13 (7)：709-719  6.Wang, X. Li, H. Qi, X. Shi, Y. Xia, Y. Yang, J. Yuan, C. Feng, X. Lin, J. Characterization and expression of a novel Frizzled 9 gene in Schistosoma japonicum. Gene Expression Patterns 2011, 11 (3-4)：263-270  7.Feng Xin-Gang,Lin Jiao-Jiao ,ZhuJian-Guo  et  al. Protective Effect Induced by Vaccination with a Partial cDNA Expression Library of Schistosoma japonicum in Mice. Chin J of Biotechnology, 2002,18(2):231-234 8.Feng Xin-gang  Tan Peiping, Yi Jianmin et al. A Preliminary Screening Of Molluscicidal Effects Of Extracts From 92 Species Of Wild Or Cultivated Plants And Chinese Herbs Against Oncomelania hupensis. Chin J of Schistosomiasis Control, 2002; 14(6):412-417 9.Feng Xingang, Yu Xinbing, Wu Zhongdao et al. A study on DNA-based immunization with eukaryotic expression recombinant plasmid containing gene encoding Schistosoma japonicum fatty acid-binding protein in Balb/c mice. Chin J Schisto Control, 2001,13(50):268-272 10.Feng Xingang, Shi Tianyi, Yi Jianming. Isolation, identification and laboratory evaluation of molluscicidal active ingredient 2-hydroxyl-3-butenyl-thioglucoside from rapeseed. Chin J Parasitol  Parasit  Dis, 2001;19（5）：318-319 11.Feng Xingang et al. Gene identification by computational methods: progress and its application to parasitic functional genomics. Parasitol fascicle in Foreign Medical Sciences , 2001; 28（5）：193-198 (review) 12.Feng Xingang, Yu Xinbing, Wu Zhongdao et al. Expression of DNA recombinant plasmid containing gene coding for cytoplasmic fatty acid-binding protein from Schistosoma japonicum in mammalian cells. Chin J Zoonoses, 2000; 16（5）：39-42 13.Feng Xingang et al. Nucleic acid vaccine and its application to control of parasitic diseases. Parasitol fascicle in Foreign Medical Sciences , 2000;27(4):150-155 (review) 14.Feng Xingang, Yu Xinbing, Wu Zhongdao et al. Amplification and cloning of the gene coding for cytoplasmic fatty acid-binding protein from Chinese Schistosoma japonicum. Chin J Zoonoses, 1999; 15（3）：33~36 15.Feng Xingang et al. Advance in study on Schistosomes cytoplasmic fatty acid-binding protein. Parasitol fascicle in Foreign Medical Sciences , 1999;26(3):104-107 (review)   16.Hu C, Zhu L, Luo R, Dao J, Zhao J, Shi Y, Li H, Lu K, Feng X, Lin J, Liu J, Cheng G. Evaluation of protective immune response in mice by vaccination the recombinant adenovirus for expressing Schistosoma japonicum inhibitor apoptosis protein. Parasitol Res. 2014 ;113(11):4261-4269. 17.Yang J, Fu Z, Feng X, Shi Y, Yuan C, Liu J, Hong Y, Li H, Lu K, Lin J. Comparison of worm development and host immune responses in natural hosts of Schistosoma japonicum, yellow cattle and water buffalo. BMC Vet Res. 2012 ;8:25. 18.Yang J, Feng X, Fu Z, Yuan C, Hong Y, Shi Y, Zhang M, Liu J, Li H, Lu K, Lin J. Ultrastructural observation and gene expression profiling of Schistosoma japonicum derived from two natural reservoir hosts, water buffalo and yellow cattle. PLoS One. 2012; 7(10):e47660. 19.Li HF, Wang XB, Jin YP, Xia YX, Feng XG, et al. Wnt4, the first member of the Wnt family identified in Schistosoma japonicum, regulates worm development by the canonical pathway. Parasitol Res (2010) 107(4): 795–805. 20.Jiang W, Hong Y, Peng J, Fu Z, Feng X, et al. Study on Differences in the Pathology, T Cell Subsets and Gene Expression in Susceptible and Non-Susceptible Hosts Infected with Schistosoma japonicum. PLoS ONE (2010) 5(10): e13494 21.Yang J, Qiu C, Xia Y, Yao L, Fu Z, Yuan C, Feng X, Lin J. Molecular cloning and functional characterization of Schistosoma japonicum enolase which is highly expressed at the schistosomulum stage. Parasitol Res. 2010; 107(3):667-77. 22.Peng J, Yang Y, Feng X, Cheng G*, Lin J*. Molecular characterizations of an inhibitor of apoptosis from Schistosoma japonicum. Parasitology Research, 2010 ;106(4):967-76